April 8, 2026 9:45 PM PDT
and the host and the on Sunday as part of the Week 8 NFL schedule. The AFC East rivals are seemingly headed in opposite directions. After a Week 7 win, the Bills are now 5-2 on the season, while the Patriots have lost three in a row to fall to 2-4 overall. William Hill lists the Bills as 4.5-point favorites, up 1.5 from the opener, and kickoff is scheduled for 1 p.m. ET.The over-under, or total number of points Vegas thinks will be scored, is 40.5 in the latest Patriots vs. Bills odds. Before you make any Bills vs. Patriots picks and NFL predictions, you should .The model, which simulates every NFL game 10,000 times, is up over $7,800 for $100 players on top-rated since its inception five-plus years ago. It's off to a strong 15-7 roll on top-rated NFL picks this season. The model also enters Week 8 on an incredible 111-72 run on top-rated NFL picks that dates back to the 2017 season.The model ranked in the Top 10 on NFLPickWatch three of the past four years on straight Mike Yastrzemski Jersey -up NFL picks and beat more than 95 percent of CBS Sports office pool players three times during that span. Anyone who has followed it is way up.Now, the model has set its sights on . You can . Now, here are several and trends for Bills vs. Patriots: Patriots vs. Bills spread: Bills -4.5Patriots vs. Bills over-under: 40.5 points Patriots vs. Bills money line: Bills -215, Patriots +185 NE: Patriots are 2-4 against the spread this season BUF: Over has hit in four of six Bills games this seasonWhy the Patriots can cover New England should be able to hold up against a Buffalo rushing attack that ranks third-worst in the NFL (97.0 yards per game), and third down defense could also bring an advantage for the Patriots. The Bills are explosive offensively, but New England is above-average in holding opponents to a 37.7 percent conversion rate on third down, and getting off the field will be crucial.Offensively, the Patriots are efficient and effective in moving the chains via the run, averaging 155.0 yards per game on the ground. The Bills are also poor on third down defensively, allowing a 50.6 percent conversion rate, and the presence of Cam Newton as a dual-threat quarterback could unlock New England's offense in this matchup.Finally, the Bills are just 12 of 17 on field goals this season, ranking near the bottom of the NFL in kicking accuracy.Why the Bills can cover The Bills bring a high-powered offense to the table, led by an explosive pa sing attack. Buffalo quarterback Josh Allen has 2,018 pa sing yards already this season with 16 touchdowns and only four interceptions. He ranks fourth in the NFL in both pa sing yards and touchdowns, and is also a threat on the ground, with 1,345 rushing yards and 20 touchdowns in only 35 career games.Buffalo is also elite at moving the chains on offense, converting 52.4 percent of third-down opportunities. Defensively, Buffalo has regre sed from its strong form in 2019, but this is a favorable matchup. The Patriots are last in the NFL in both pa sing touchdowns (three) and interceptions thrown (11), while New England also ranks in a tie for last in quarterback rating (65.1) and in the bottom five in pa sing offense (197.2 yards per game).How to make Patriots vs. Bills picks SportsLine's model is leaning Over on the total, with both teams projected to average more than 4.5 yards per carry. The model also says one side of the spread hits in over 50 percent of simulations. .So who wins Patriots vs. Bills? And which side of the spread hits in over 50 percent of simulations? , and find out. Brandon Crawford Jersey
and the host and the on Sunday as part of the Week 8 NFL schedule. The AFC East rivals are seemingly headed in opposite directions. After a Week 7 win, the Bills are now 5-2 on the season, while the Patriots have lost three in a row to fall to 2-4 overall. William Hill lists the Bills as 4.5-point favorites, up 1.5 from the opener, and kickoff is scheduled for 1 p.m. ET.The over-under, or total number of points Vegas thinks will be scored, is 40.5 in the latest Patriots vs. Bills odds. Before you make any Bills vs. Patriots picks and NFL predictions, you should .The model, which simulates every NFL game 10,000 times, is up over $7,800 for $100 players on top-rated since its inception five-plus years ago. It's off to a strong 15-7 roll on top-rated NFL picks this season. The model also enters Week 8 on an incredible 111-72 run on top-rated NFL picks that dates back to the 2017 season.The model ranked in the Top 10 on NFLPickWatch three of the past four years on straight Mike Yastrzemski Jersey -up NFL picks and beat more than 95 percent of CBS Sports office pool players three times during that span. Anyone who has followed it is way up.Now, the model has set its sights on . You can . Now, here are several and trends for Bills vs. Patriots: Patriots vs. Bills spread: Bills -4.5Patriots vs. Bills over-under: 40.5 points Patriots vs. Bills money line: Bills -215, Patriots +185 NE: Patriots are 2-4 against the spread this season BUF: Over has hit in four of six Bills games this seasonWhy the Patriots can cover New England should be able to hold up against a Buffalo rushing attack that ranks third-worst in the NFL (97.0 yards per game), and third down defense could also bring an advantage for the Patriots. The Bills are explosive offensively, but New England is above-average in holding opponents to a 37.7 percent conversion rate on third down, and getting off the field will be crucial.Offensively, the Patriots are efficient and effective in moving the chains via the run, averaging 155.0 yards per game on the ground. The Bills are also poor on third down defensively, allowing a 50.6 percent conversion rate, and the presence of Cam Newton as a dual-threat quarterback could unlock New England's offense in this matchup.Finally, the Bills are just 12 of 17 on field goals this season, ranking near the bottom of the NFL in kicking accuracy.Why the Bills can cover The Bills bring a high-powered offense to the table, led by an explosive pa sing attack. Buffalo quarterback Josh Allen has 2,018 pa sing yards already this season with 16 touchdowns and only four interceptions. He ranks fourth in the NFL in both pa sing yards and touchdowns, and is also a threat on the ground, with 1,345 rushing yards and 20 touchdowns in only 35 career games.Buffalo is also elite at moving the chains on offense, converting 52.4 percent of third-down opportunities. Defensively, Buffalo has regre sed from its strong form in 2019, but this is a favorable matchup. The Patriots are last in the NFL in both pa sing touchdowns (three) and interceptions thrown (11), while New England also ranks in a tie for last in quarterback rating (65.1) and in the bottom five in pa sing offense (197.2 yards per game).How to make Patriots vs. Bills picks SportsLine's model is leaning Over on the total, with both teams projected to average more than 4.5 yards per carry. The model also says one side of the spread hits in over 50 percent of simulations. .So who wins Patriots vs. Bills? And which side of the spread hits in over 50 percent of simulations? , and find out. Brandon Crawford Jersey