Why is CtBP1 considered a significant target in cancer research and antibody development?

  • March 18, 2026 12:35 AM PDT

    Research has shown that CtBP1 is often overexpressed in various malignancies, where it promotes the epithelial-mesenchymal transition (EMT) and tumor cell survival. Developing high-affinity antibodies for targeting CtBP1 in cancer therapy is essential for understanding how to counteract its role in suppressing tumor-suppressive genes.